Published

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原著論文

Peer-Reviewed Original Papers

2024年

  • Kohei Kawaguchi, Tamaki Maeda, Syuuhei Komatsu, Yoshihiro Nomurac and Kazuki Murai
    Formation mechanism of anisotropic gelatin hydrogel by self-assembly on oriented templates?
    Mol. Syst. Des. Eng., 2024,9, 561-570. DOI:https://doi.org/10.1039/D4ME00023D
    (Front cover: Mol. Syst. Des. Eng., 2024)
    https://pubs.rsc.org/en/content/articlelanding/2024/me/d4me00023d

  • Syuuhei Komatsu, Satoshi Yamada, Akihiko Kikuchi,
    Preparation of Degradable and Transformable Core–Corona-Type Particles that Control Cellular Uptake by Thermal Shape Change,
    ACS Biomter. Sci. Eng., 2024, 10, 897-904.DOI: 10.1021/acsbiomaterials.3c01554
    (Supplementary Cover: ACS Biomater. Sci. Eng., 2024)
    https://pubs.acs.org/toc/abseba/10/2

  • Yuya Yoshida, Manami Aoki, Kalin Nagase, Koichi Marubashi, Hiroyuki Kojima,
    Shoko Itakura, Syuuhei Komatsu, Kenji Sugibayashi, Hiroaki Todo
    Plasmid DNA Delivery into the Skin via Electroporation with a Depot-Type Electrode
    2024 Sep 18;16(9):1219. doi: 10.3390/pharmaceutics16091219.PMID: 39339255
    https://pubmed.ncbi.nlm.nih.gov/39339255/

  • Manami Nomura, Junki Tomita, Shoko Itakura, Hiroaki Todo Nao Kodama, Yutaka Inoue
    Study of the preparation, characterization, and solubility of lidocaine complexed with 5-sulfosalicylic acid dihydrate
    2024 Jul;50(7):628-638. doi: 10.1080/03639045.2024.2382396. Epub 2024 Jul 28.PMID: 39030701
    https://pubmed.ncbi.nlm.nih.gov/39030701/

  • Miyu Ai, Risa Kanai, Hiroaki Todo, Junki Tomita, Takashi Tanikawa1 and Yutaka Inoue
    Characterization, stability, and skin application of astaxanthin particulates
    Published: 02 September 2024 Article number: 9 (2024)
    https://aapsopen.springeropen.com/articles/10.1186/s41120-024-00099-8

  • Daisuke Sasaki, Hinako Suzuki, Kosuke Kusamori, Shoko Itakura, Hiroaki Todo, Makiya Nishikawa
    Development of rice bran-derived nanoparticles with excellent anti-cancer activity and their application for peritoneal dissemination
    2024 Mar 16;22(1):114. doi: 10.1186/s12951-024-02381-z.PMID: 38493106
    https://pubmed.ncbi.nlm.nih.gov/38493106/

  • Ryoki Kunita, Takafumi Nishijima, Hiroaki Todo, Masaaki Miyazawa
    Integrating mathematical approaches (IMAS): Novel methodology for predicting dermal absorption rates of chemicals under finite dose conditions
    2024;49(5):219-230. doi: 10.2131/jts.49.219.PMID: 38692909
    https://pubmed.ncbi.nlm.nih.gov/38692909/

  • Flores KA, Okada A, Arce F Jr, See GL, Itakura S, Todo H, Sugibayashi K.
    Development of an Auraptene-Loaded Transdermal Formulation Using Non-ionic Sugar Ester Surfactants. Chem Pharm Bull. 2024,72(3):319-323. doi: 10.1248/cpb.c23-00796. PMID: 38508724.
    https://www.jstage.jst.go.jp/article/cpb/72/3/72_c23-00796/_article

  • Futaki M, Inamura K, Nishimura T, Niitsu T, Tojo T, Sugibayashi K, Todo H.
    A Hollow Microneedle Equipped with a Micropillar for Improved Needle Insertion and Injection of Drug Solution.Pharm Res.
    2024 Mar 5. doi: 10.1007/s11095-024-03681-7. Online ahead of print.
    https://link.springer.com/article/10.1007/s11095-024-03681-7

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2023年

  • Inoue Y, Ueda S, Tanikawa T, Sano A, Suzuki R, Todo H, Higuchi Y, Akao K.
    Characterization of Carbohydrates, Amino Acids, Viscosity, and Antioxidant Capacity in Rice Wines Made in Saitama, Japan, with Different Sake Rice.,Foods. 2023 Nov 1;12(21):4004. doi: 10.3390/foods12214004.PMID: 37959123 Free PMC article.
    https://www.mdpi.com/2304-8158/12/21/4004

  • Niki Rina, Akie Okada, Hiroaki Todo, Ibuki Narita, Kazuya inamura,Shoko itakura,Ichiro Hijikuro and Kenji Sugibayashi,
    Development of a depot formulation with an in situ non-lamellar liquid crystal-forming system with phospholipids.,Front. Drug Deliv, 19 October 2023
    https://www.frontiersin.org/articles/10.3389/fddev.2023.1270584/full

  • Futaki M, Inamura K, Hashimoto M, Motegi S, Itakura S, Sugibayashi K, Todo H.
    Effects of Intradermal Administration Volume Using a Hollow Microneedle on the Pharmacokinetics of Fluorescein Isothiocyanate Dextran (M.W. 4,000).,Pharm Res. 2023 May 10. doi: 10.1007/s11095-023-03529-6. Online ahead of print.,PMID: 37165148
    https://link.springer.com/article/10.1007/s11095-023-03529-6

  • Sugibayashi K.
    The role of higher education in pharmacy and pharmaceutical sciences in addressing global warming: A personal perspective.,JOURNAL OF ASIAN ASSOCIATION OF SCHOOLS OF PHARMACY- Volume 12, January - December 2023.,Pages: 38-46
    https://link.springer.com/article/10.1007/s11095-023-03529-6

  • Sekiguchi S,Narita I,Itakura S,Kojima H,Sugibayashi K,Todo H.
    Evaluation of Skin Permeation Order of Cosmetic Active Compoundsfrom Commercially Available Cosmetic Products with Different Dosage Forms Using a Three-Dimensional Cultured Human Skin Model.,Accepted: June 2, 2023
    https://jcss.jp/journal/pdf/4703/47-3_176.pdf

  • Takayama K, Itakura S, Todo H, Sugibayashi K.
    Prediction of Critical Quality Attributes Based on the Numerical Simulation of Stress and Strain Distributions in Pharmaceutical Tablets.,ChemPharm Bull (Tokyo). 2023;71(6):386-397. doi: 10.1248/cpb.c22-00539.,PMID: 37258191
    https://www.jstage.jst.go.jp/article/cpb/71/6/71_c22-00539/_html/-char/en

  • Takayama K, Itakura S, Todo H, Sugibayashi K.
    Prediction of Critical Quality Attributes Based on the Numerical Simulation of Stress and Strain Distributions in Pharmaceutical Tablets.,Chem Pharm Bull (Tokyo). 2023;71(6):386-397. doi: 10.1248/cpb.c22-00539.
    https://pubmed.ncbi.nlm.nih.gov/37258191/

  • Oshizaka T, Hayakawa M, Uesaka M, Yoshizawa K, Kamei T, Takeuchi I, Mori K, Itakura S, Todo H,Sugibayashi K.
    Design of an Ante-enhancer with an Azone-Mimic Structure using Ionic Liquid.Pharm Res. 2023 Apr 20. doi: 10.1007/s11095-023-03515-y. Online ahead of print.
    https://link.springer.com/article/10.1007/s11095-023-03515-y

  • Itakura S, Shohji A, Amagai S, Kitamura M, Takayama K, Sugibayashi K, Todo H.
    Gene knockdown in HaCaT cells by small interfering RNAs entrapped in grapefruit-derived extracellular vesicles using a microfluidic device.,Sci.Rep.,2023 Feb 22;13(1):3102.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947018/

  • Mori K, Yamazaki K, Takei C, Oshizaka T, Takeuchi I, Miyaji K, Todo H, Itakura S, Sugibayashi K.
    Remote-controllable dosage management through a wearable iontophoretic patch utilizing a cell phone.,J. Control.Release 2023 Mar;355:1-6.
    https://www.sciencedirect.com/science/article/pii/S016836592300055X

  • Kojima H, Nakada T, Yagami A, Todo H, Nishimura J, Yagi M, Yamamoto K, Sugiyama M, Ikarashi Y, Sakaguchi H, Yamaguchi M, Hirota M, Aizawa S, Nakagawa S, Hagino S, Hatao M.
    A step-by-step approach for assessing acute oral toxicity without animal testing for additives of quasi-drugs and cosmetic ingredients,Curr Res Toxicol. 2022 Dec 23;4:100100. eCollection 2023.
    https://pure.fujita-hu.ac.jp/en/publications/a-step-by-step-approach-for-assessing-acute-oral-toxicity-without

  • Ito A, Itakura S,Hasegawa Y,Hashimoto M,Okada A, Hirafuji M,Nakamura H,Sugibayashi K an, Todo H.
    Usefulness of direct intratumoral administration of doxorubicin hydrochloride with an electro-osmosis–assisted pump ,Front. Drug Deliv, 04 April 2023
    https://www.frontiersin.org/articles/10.3389/fddev.2023.1150894/full

2022年

  • Inoue Y, Ishizawa M, Itakura S, Tanikawa T, Todo H.
    Verification of nanoparticle formation, skin permeation, and apoptosis using Nobiletin as a methoxyflavonoid derivative, AAPS Open, 8, 17 (2022).
    https://aapsopen.springeropen.com/articles/10.1186/s41120-022-00065-2

  • Sakurai H, Suzuki M, Itakura S, Todo H, Arce F V Jr, See GL, Tanikawa T, Inoue Y.
    Preparation, Characterization, Solubility, and Antioxidant Capacity of Ellagic Acid-Urea Complex, Materials,15, 2836 (2022)
    https://www.mdpi.com/1996-1944/15/8/2836

  • 藤堂浩明.
    半固形製剤からの薬物の経皮吸収についての考え方 (半固形製剤特集),製剤機械技術学会会誌, 31, 16-24 (2022).

  • Ono N, Iibuchi T, Todo H, Itakura S, Adachi H, Sugibayashi K.
    Enhancement of skin permeation of fluorescein isothiocyanate-dextran 4 kDa (FD4) and insulin by thermalporation, Eur. J.Pharm. Sci., 170, 106096 (2022).
    https://www.sciencedirect.com/science/article/pii/S0928098721003973?via%3Dihub

  • Hama S, Nishi T, Isono E, Itakura S, Yoshikawa Y, Nishimoto A, Suzuki S, Kirimura N, Todo H, Kogure K.
    Intraperitoneal administration of nanoparticles containing tocopheryl succinate prevents peritoneal dissemination.Cancer Sci.,113, 1779-1788 (2022).
    https://onlinelibrary.wiley.com/doi/10.1111/cas.15321

  • Okada A, Niki R, Inoue Y, Tomita J, Todo H, Itakura S, Sugibayashi K.
    Development of Self-Administered Formulation to Improve the Bioavailability of Leuprorelin Acetate.(2022)
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031317/

  • Kunita R, Nishijima T, Todo H, Sugibayashi K, Sakaguchi H.
    A Mathematical Approach Using Strat-M? to Predict the Percutaneous Absorption of Chemicals under Finite Dose Conditions.(2022)
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318111/

  • Kojima H, Nakada T, Yagami A, Todo H, Nishimura J, Yagi M, Yamamoto K, Sugiyama M, Ikarashi Y, Sakaguchi H, Yamaguchi M, Hirota M, Aizawa S, Nakagawa S, Hagino S, Hatao M.
    A step-by-step approach for assessing acute oral toxicity without animal testing for additives of quasi-drugs and cosmetic ingredients.(2022)
    https://www.sciencedirect.com/science/article/pii/S2666027X22000378?via%3Dihub

  • Sano T, Okada A, Kawasaki K, Kume T, Fukui M, Todo H, Sugibayashi K.
    Self-Assembled Structure of α-Isostearyl Glyceryl Ether Affects Skin Permeability-a Lamellar with 70-nm Spaces and L3 Phase Enhanced the Transdermal Delivery of a Hydrophilic Model Drug.(2022)
    https://link.springer.com/article/10.1208/s12249-022-02452-0

  • Kamimura M, Inui T, Mouri A, Todo H, Sugibayashi K, Asano K.
    A Pilot Study of Transdermal Application of Diphenhydramine to the Nasal Ala in Patients with Allergic Rhinitis and Asthma.(2022)
    https://pubmed.ncbi.nlm.nih.gov/36420548/

2021年

2020年

  • Sugibayashi K, Yamamoto N, Itakura S, Okada A, Hijikuro I, Todo H.
    Development of spray formulations applied to the oral mucosa using non-lamellar liquid crystal-forming lipids,Chem Pharm Bull,68, 1025-1033 (2020).
    https://www.jstage.jst.go.jp/article/cpb/68/11/68_c20-00333/_html/-char/en

  • 杉林 堅次, 森 健二, 押坂 勇志, 武井 千弥, 藤堂 浩明, 板倉 祥子, 高山 幸三.
    感染から治癒過程を表現する「感染症数理疫学」と吸収から消失過程を表現する「薬物動態学」の類似点と相違点.薬剤学, 80 , 322-329 (2020).
    https://www.jstage.jst.go.jp/article/jpstj/80/6/80_322/_pdf

  • See GL, Arce F Jr, Dahlizar S, Okada A, Fadli MFBM, Hijikuro I, Itakura S, Katakura M, Todo H, Sugibayashi K.
    Enhanced Nose-To-Brain Delivery of Tranilast Using Liquid Crystal Formulations.J. Control. Release, 325, 1-9 (2020).
    https://pubmed.ncbi.nlm.nih.gov/32598958/

  • Abe A., Suzuki H., Saito M., Todo H., Sugibayashi K.
    Effect of rubbing on the distribution of topically applied drugs into the hair follicles. Chemical and Pharmaceutical Bulletin, 68,832-836(2020).
    https://www.jstage.jst.go.jp/article/cpb/68/9/68_c20-00061/_html/-char/en

  • See GL, Arce F Jr, Itakura S, Todo H, Sugibayashi K.
    Prolonged distribution of tranilast in the eyes after topical application onto eyelid skin. Chemical and Pharmaceutical Bulletin, 68,779-783(2020).
    https://www.jstage.jst.go.jp/article/cpb/68/8/68_c20-00289/_html/-char/ja

  • Sugibayashi K, Yoshida Y, Suzuki R, Yoshizawa K, Mori K, Itakura S, Takayama K, Todo H.
    Physical Properties of an Ionic Liquid Composed of Two Water-Soluble Vitamins and Enhanced Skin Permeation of Both Vitamins. Pharmaceutics.12(5):E427 (2020).
    https://www.mdpi.com/1999-4923/12/5/427

  • Arce F Jr, Asano N, See GL, Oshizaka T, Itakura S, Todo H, Sugibayashi K.
    Prediction of skin permeation and concentration of rhododendrol applied as finite dose from complex cosmetic vehicles.Int J Pharm., 578, 119186. (2020).
    https://pubmed.ncbi.nlm.nih.gov/32112931/

  • Arce FJ, Asano N, See GL, Itakura S, Todo H, Sugibayashi K.
    Usefulness of Artificial Membrane, Strat-M?, in the Assessment of Drug Permeation from Complex Vehicles in Finite Dose Conditions.Pharmaceutics, 12. 173 (2020)．
    https://www.mdpi.com/1999-4923/12/2/173

  • Okada A, Todo H, Hijikuro I, Itakura S, Sugibayashi K.
    Controlled release of a model hydrophilic high mollecular weight compound from injectble non-lamellar liquid crystal formulations containing different types of phospholipids.,Int.J.Pharm.,577, 118944 (2020).
    https://pubmed.ncbi.nlm.nih.gov/31870952/

2019年

  • Iikura H, Uchida K, Ogawa-Fuse C, Bito K, Naitou S, Hosokawa M, Uchida T, Sano T, Todo H, Sugibayashi K.
    Effects of temperature and humidity on the skin permeation of hydrophilic and hydrophobic drugs, AAPS PharmSciTech, 20, 264 (2019)
    https://pubmed.ncbi.nlm.nih.gov/31342293/
  • 藤堂浩明， 足立浩章， 今井教安， 上中麻規子， 内田崇志， 大谷道輝， 澤田美月， 成田昌稔， 西島貴史， 野村宜史， 宮坂美行， 畑尾正人， 増永卓司， 山口雅彦， 佐々齊， 知久真巳， 川田裕三， 古屋律子， 藤井まき子.
    無限用量にて適用した種々剤形からのカフェインの皮膚透過性と皮膚内濃度の関係について—ヒト長期投与 (安全性) 試験の用量設定法ガイドライン策定のための検証結果 その 2—,日本香粧品学会誌, 43, 183-190 (2019).
    https://www.jstage.jst.go.jp/article/koshohin/43/3/43_430301/_pdf

  • Sugibayashi K, Yusuf E, Todo H, Dahlizar S, Sakdiset P, Arce FV Jr, See GL.
    Halal cosmetics: A review on ingredients, production, and testing methods, Cosmetics, 6, 37 (2019)
    https://www.mdpi.com/2079-9284/6/3/37

  • Hatanaka T, Saito T, Fukushima T, Todo H, Sugibayashi K, Umehara S, Takeuchi T, Okamura Y.
    Potential of biocompatible polymeric ultra-thin films, nanosheets, as topical and transdermal drug delivery devices, Int J Pharm, 565, 41-49 (2019).
    https://pubmed.ncbi.nlm.nih.gov/31022503/
  • 藤堂浩明， 足立浩章， 今井教安， 上中麻規子， 内田崇志， 大谷道輝， 澤田美月， 成田昌稔， 西島貴史， 野村宜史， 宮坂美行， 畑尾正人， 増永卓司， 山口雅彦， 佐々齊， 知久真巳， 川田裕三， 古屋律子， 藤井まき子.
    無限用量にて適用した種々剤形からのイソプロピルメチルフェノールの皮膚透過性と皮膚内濃度の関係について—ヒト長期投与 (安全性) 試験の用量設定法ガイドライン策定のための検証結果 その 1—, 日本香粧品学会誌,43, 99-108 (2019).
    https://www.jstage.jst.go.jp/article/koshohin/43/2/43_430202/_pdf
  • Okada A, Todo H, Hijikuro I, Itakura S, Sugibayashi K.
    Controlled release of a model hydrophilic high mollecular weight compound from injectble non-lamellar liquid crystal formulations containing different types of phospholipids, Int. J. Pharm, (2019) Dec 21:118944 .
    https://pubmed.ncbi.nlm.nih.gov/31870952/

  • Sugibayashi K, Yusyf E, Todo H, Dahlizar S, Sakdiset P, Arce F.V.J,SeeG.L.
    A Review on Ingredients, Production, and Testing Methods, Cosmetics (2019), 6, x.
    https://www.mdpi.com/2079-9284/6/3/37

  • Takamaya K, Sato T, Sato K, Todo H, Obata Y, Sugibayashi K.
    Prediction of tablet characteristics based on sparse modeling for residual stresses simulated by the finite element method incorporating Drucker-Prager cap model,JDDST ,52, 1021-1031 (2019).
    https://www.sciencedirect.com/science/article/pii/S1773224718314205

  • See G.L, Sagesaka A, Todo H, Wierzba K, Sugibayashi K.
    Pharmacokinetics and Tissue Distribution of Pilocarpine After Application to Eyelid Skin of Rats, J. Pharm. Sci., 108, 2942-2948 (2019).
    https://jpharmsci.org/article/S0022-3549(19)30240-0/pdf
  • Arce FV Jr, Asano N, Yamashita K, Oda A, Uchida T, Sano T, Todo H, Sugibayashi K.
    Effect of layered application on the skin permeation of a cosmetic active component, rhododendrol. J Toxicol Sci.44, 1-11 (2019).
    https://www.jstage.jst.go.jp/article/jts/44/1/44_1/_html/-char/en

2018年

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